The purposes of the research study were: 1) to design the gamification learning environment with block-based programming to enhance system thinking in grade 9. 2) to study the ability in system thinking of student after using the gamification learning environment with block-based programming The samples of the research were 30 students who study at Ongkharak Demonstration School, Srinakharinwirot University during academic year 2019. The research tools were 1) the gamification learning environment with block-based programming and 2) The system thinking evaluation form. The findings were as follows: 1) the gamification learning environment with block-based programming to enhance system thinking in grade 9 consists of 1) Game Mechanics and Game Dynamics 2) block-based programming lesson plan. 2) The comparation result of the system thinking of students before with after studying with gamification learning environment with block-based programming showed that students who study with said environment have higher score at .05 level, considering as high level of system thinking ability.