This study aims to evaluate the impact of the Covid-19 epidemic on travel activities in Can Tho City, thereby suggesting solutions to cope with the impact of Covid-19 on travel activities. The study used the questionnaire interview method to get the expected results. The results show that, under the impact of the Covid-19 epidemic, travel companies have been severely affected in terms of number of visitors, revenue, capacity and personnel. Since then, leading to some tour operators having to operate in moderation, temporarily closing down and more strictly the company collapsed. Those most affected are business owners. The problem of business costs, many taxes, jobs for employees, salaries for employees, etc. is really a difficult problem that travel companies are facing. The study also proposes solutions for tourism recovery in the coming time of travel agencies.